With the fixed loop injector, the TruView Pre-Slit, Lectrabond pre-split and Lectrabond Solid septa gave better resealibility across the multiple injections and longer time periods. For the flow through needle Injector (FTN), there was much less difference among the different septa, with the TrueView Solid, Lectrabond Solid, LCMS Pre-Split and LCMS Solid septa performing best.