The Role of PTFE Septa in Minimizing Sample Contamination in Nutraceutical Analysis

The septum forms a barrier between your sample analyte in the vial and the outside atmosphere. This barrier protects your sample from external contamination while allowing a needle (from a manual or automatic syringe) to enter the vial, and extract the sample for the next stage of separation.

Jan 2, 2006 · Figure 3 - Typical mass chromatogram of volatile residue in hexane caused by PTFE/silicone septa: a) hexane extract of a piece of septum; b) vial septum was punctured once by a syringe to sample 1 μL hexane for GC analysis; c) hexane in the last vial was reanalyzed after 3 days; and d) analyzed immediately after 100 μL hexane was added from one vial to another (the septum was punctured 10

With respect to semiclosed systems, a PTFE apparatus generating HF vapor has been specifically designed to minimize contamination during trace-element determination of ultrapure silicon, quartz, and glass . The sample is placed in a PTFE beaker mounted on a perforated PTFE plate that is kept above the level of liquid HF in the chamber.

With this growth, come many more analytical challenges. For all nutraceuticals, the compositional quality and safety must be monitored to track contamination, adulteration, product consistency, and to ensure regulatory compliance. Thermo Fisher Scientific is a recognized leader in providing analytical solutions for sample preparation, liquid

Boston round clear Type III glass bottles feature caps for the 125 and 250 mL sizes that are ultrasonically bonded with a 0.125” PTFE-lined, silicone liner. Caps for the 500 and 1000 mL sizes are equipped with a friction-fit PTFE liner which be easily replaced if necessary. Bottles have a. Compare this item.

Our closures with septa are made in a wide variety of sizes and materials ensuring you have the right combination for your sample type and analysis temperature. 9 mm Pre-Assembled Blue Polypropylene Screw Cap with Pre-Slit PTFE/Silicone Septa, 100/pk | PerkinElmer

grade polyethylene does not have the contamination issues PTFE/Silicone septa show at low levels of detection, while also sealing exceptionally well. The Pico Pure cap will puncture with far less force than needed to puncture a PTFE/Silicone septa, thus minimizing instrument wear and tear as well as downtime.

Jun 9, 2022 · Siloxane contamination can interfere with low-level analysis of target compounds whether they are discrete peaks or manifested as high background bleed. They are one of the most common types of “ghost peaks” in gas chromatography (GC) and can come from a variety of sources such as inlet septa, columns, valves, solvents, and vial cap seals.

white PTFE/red Silicone septa, 11mm crimp-top aluminum cap,5.5mm centre hole pre-slit white PTFE/red Silicone septa, 11mm crimp-top aluminum cap,5.5mm centre hole Non-slip Nature PTFE/White Silicone septa,11 mm crimp -top aluminum cap, 5.5 mm centre hole 100pcs/pk 100pcs/pk Model No. Description IPA150 IPB250 IA250 IA250 IPB250 IB300 IB300 V18A

The septum is provided with a thin 0.005” PTFE layer laminated to highly pure silicone, and slit through the center for easier needle penetration and to release the vacuum that forms when a large volume of sample is withdrawn from a vial.

With respect to semiclosed systems, a PTFE apparatus generating HF vapor has been specifically designed to minimize contamination during trace-element determination of ultrapure silicon, quartz, and glass . The sample is placed in a PTFE beaker mounted on a perforated PTFE plate that is kept above the level of liquid HF in the chamber.

Mar 6, 2020 · XPS is an important tool for understanding the nature of NP surfaces as well as the structure and thickness of coatings on NPs. It can be used in different ways to extract important information including the composition of the NPs, presence of contamination, the consistency of functionalization, the quantity of adsorbates on surfaces, and the thicknesses of layers and coatings. 2,16–19 The

It’s easy to think of vials as simple, inexpensive components that don’t affect your results. However, substandard vials, caps, and septa can lead to sample loss, contamination, and damaged autosampler needles. Aijiren understands that vials are a critical part of your analytical workflow—no less important than the column or the instrument.

The sample preparation procedure should be specified in the sample analysis procedure and should be included as part of the sample and analysis plan (SAP) or QAPP. This procedure should demonstrate that extreme care is taken to prevent sample contamination during preparation and extraction.

Select Level 3 products for ultimate performance and sensitivity from your methods, while maintaining the highest levels of sample security and integrity. Choose from a variety of kits containing short thread screw vials with marking spots in clear or amber glass and polypropylene caps with silicone/PTFE septa designed to reduce autosampler